Lipidology

15
Featured Session · 15 of 35

Lipidology

Lipidology has moved well beyond statins. Sessions cover combination LDL-lowering with ezetimibe, bempedoic acid and PCSK9 inhibitors (alirocumab, evolocumab, inclisiran, MK-0616 oral PCSK9), Lp(a) lowering with olpasiran, lepodisiran, pelacarsen and muvalaplin, triglyceride therapies including icosapent ethyl and emerging APOC3 / ANGPTL3 targets, familial hypercholesterolaemia pathways, and the role of CRISPR base-editing for durable single-dose LDL reduction. Discussion includes primary-care integration, residual risk and lifetime-prevention strategy.

Topics covered in this session
  • PCSK9 inhibitors (mAb, siRNA, oral)
  • Lp(a) lowering: olpasiran, lepodisiran, muvalaplin
  • Bempedoic acid and combination therapy
  • Triglyceride therapies and APOC3 targets
  • Familial hypercholesterolaemia
  • CRISPR base editing for LDL
  • Residual risk and lifetime prevention
  • Primary-care integration